This study focuses on screening algal strains from a vast microalgal library for their tolerance to various types of industrial wastewater. By combining these strains with symbiotic bacteria with enhanced functional capabilities, the team has developed innovative microbial formulations capable of efficiently treating pre-processed wastewater. Pre-treatment involves chemical treatment and precipitation to remove large amounts of impurities and toxic substances, as well as adjustment of extreme pH values. The microbial formulations can rapidly remove organic carbon, nitrogen, phosphorus, inorganic nitrogen sources, and metal ions, significantly reducing the use of chemical reagents and the volume of water required for dilution during treatment. As a result, wastewater discharge, conductivity, and sludge generation are all substantially decreased. Currently, most wastewater treatment companies in Taiwan rely primarily on equipment-based and chemical treatment methods. Even after conventional treatment, trace amounts of organic and inorganic compounds often remain in the effluent, requiring further removal or recovery. In response to changing environmental conditions and emerging needs, our team has developed a range of biologically based water treatment formulations, representing a microcosm of the international development trajectory in wastewater treatment technologies. Through the development and application of these algal-bacterial treatment systems, the research provides insights into the current state and future trends of water treatment technology, helping to address evolving environmental challenges and future demands.